Hepatitis aguda por virus E con características de autoinmunidad. Reporte de un caso

We analyze the case of a 49-year-old male patient who presented with clinical signs acute hepatitis an initial suspicion autoimmune etiology. Laboratory findings demonstrated positive antinuclear antibody, anti-smooth muscle antibody and high serum gamma globulin. Histology liver biopsy revealed changes compatible hepatitis, which associated International Autoimmune Hepatitis Group score 7, determined initiation treatment Meprednisolone Azathioprine. During follow-up, we received serological results immunoglobulin M against E virus detectable viremia by reverse transcription polymerase chain reaction technique, changing diagnosis to secondary virus. Immunosuppression was suspended continued biochemical improvement. In Argentina, testing is not routinely performed, however, avoid misdiagnosis, this etiology should be ruled out in patients before labeling it as hepatitis. This could reduce unnecessary that endanger our patients.